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Postnatal loss of the insulin receptor in osteoprogenitor cells does not impart a metabolic phenotype

The relationship between osteoblast-specific insulin signaling, osteocalcin activation and gluco-metabolic homeostasis has proven to be complex and potentially inconsistent across animal-model systems and in humans. Moreover, the impact of postnatally acquired, osteoblast-specific insulin deficiency...

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Detalles Bibliográficos
Autores principales: Fowlkes, John L., Clay Bunn, R., Kalaitzoglou, Evangelia, Ray, Phil, Popescu, Iuliana, Thrailkill, Kathryn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264347/
https://www.ncbi.nlm.nih.gov/pubmed/32483283
http://dx.doi.org/10.1038/s41598-020-65717-3