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An evolutionary path to altered cofactor specificity in a metalloenzyme

Almost half of all enzymes utilize a metal cofactor. However, the features that dictate the metal utilized by metalloenzymes are poorly understood, limiting our ability to manipulate these enzymes for industrial and health-associated applications. The ubiquitous iron/manganese superoxide dismutase (...

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Detalles Bibliográficos
Autores principales: Barwinska-Sendra, Anna, Garcia, Yuritzi M., Sendra, Kacper M., Baslé, Arnaud, Mackenzie, Eilidh S., Tarrant, Emma, Card, Patrick, Tabares, Leandro C., Bicep, Cédric, Un, Sun, Kehl-Fie, Thomas E., Waldron, Kevin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264356/
https://www.ncbi.nlm.nih.gov/pubmed/32483131
http://dx.doi.org/10.1038/s41467-020-16478-0