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Partial proteolysis improves the identification of the extracellular segments of transmembrane proteins by surface biotinylation

Transmembrane proteins (TMP) play a crucial role in several physiological processes. Despite their importance and diversity, only a few TMP structures have been determined by high-resolution protein structure characterization methods so far. Due to the low number of determined TMP structures, the pa...

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Detalles Bibliográficos
Autores principales: Langó, Tamás, Pataki, Zoltán Gergő, Turiák, Lilla, Ács, András, Varga, Julia Kornélia, Várady, György, Kucsma, Nóra, Drahos, László, Tusnády, Gábor E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264363/
https://www.ncbi.nlm.nih.gov/pubmed/32483232
http://dx.doi.org/10.1038/s41598-020-65831-2