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HCN2 Channel-Induced Rescue of Brain Teratogenesis via Local and Long-Range Bioelectric Repair

Embryonic exposure to the teratogen nicotine results in brain defects, by disrupting endogenous spatial pre patterns necessary for normal brain size and patterning. Extending prior work in Xenopus laevis that showed that misexpression of ion channels can rescue morphogenesis, we demonstrate and char...

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Detalles Bibliográficos
Autores principales: Pai, Vaibhav P., Cervera, Javier, Mafe, Salvador, Willocq, Valerie, Lederer, Emma K., Levin, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264377/
https://www.ncbi.nlm.nih.gov/pubmed/32528251
http://dx.doi.org/10.3389/fncel.2020.00136