Variability in Genome Editing Outcomes: Challenges for Research Reproducibility and Clinical Safety

Genome editing tools have already revolutionized biomedical research and are also expected to have an important impact in the clinic. However, their extensive use in research has revealed much unpredictability, both off and on target, in the outcome of their application. We discuss the challenges as...

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Detalles Bibliográficos
Autores principales: Teboul, Lydia, Herault, Yann, Wells, Sara, Qasim, Waseem, Pavlovic, Guillaume
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264426/
https://www.ncbi.nlm.nih.gov/pubmed/32243835
http://dx.doi.org/10.1016/j.ymthe.2020.03.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264426/
https://www.ncbi.nlm.nih.gov/pubmed/32243835
http://dx.doi.org/10.1016/j.ymthe.2020.03.015

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