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Variability in Genome Editing Outcomes: Challenges for Research Reproducibility and Clinical Safety
Genome editing tools have already revolutionized biomedical research and are also expected to have an important impact in the clinic. However, their extensive use in research has revealed much unpredictability, both off and on target, in the outcome of their application. We discuss the challenges as...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society of Gene & Cell Therapy
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264426/ https://www.ncbi.nlm.nih.gov/pubmed/32243835 http://dx.doi.org/10.1016/j.ymthe.2020.03.015 |