Tsg101 positively regulates P62-Keap1-Nrf2 pathway to protect hearts against oxidative damage

Currently, most antioxidants do not show any favorable clinical outcomes in reducing myocardial ischemia-reperfusion (I/R) injury, suggesting an urgent need for exploring a new regulator of redox homeostasis in I/R hearts. Here, using heart-specific transgenic (TG) and knockdown (KD) mouse models, t...

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Detalles Bibliográficos
Autores principales: Deng, Shan, Essandoh, Kobina, Wang, Xiaohong, Li, Yutian, Huang, Wei, Chen, Jing, Peng, Jiangtong, Jiang, Ding-Sheng, Mu, Xingjiang, Wang, Chenran, Peng, Tianqing, Guan, Jun-Lin, Wang, Yigang, Jegga, Anil, Huang, Kai, Fan, Guo-Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264471/
https://www.ncbi.nlm.nih.gov/pubmed/32057709
http://dx.doi.org/10.1016/j.redox.2020.101453

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264471/
https://www.ncbi.nlm.nih.gov/pubmed/32057709
http://dx.doi.org/10.1016/j.redox.2020.101453

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