CD40 agonist-induced IL-12p40 potentiates hepatotoxicity

BACKGROUND: CD40 is a compelling target for cancer immunotherapy, however, attempts to successfully target this pathway have consistently been hampered by dose-limiting toxicity issues in the clinic that prevents the administration of efficacious doses. METHODS: Here, using cytokine and cytokine rec...

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Detalles Bibliográficos
Autores principales: Bonnans, Caroline, Thomas, Graham, He, Wenqian, Jung, Breanna, Chen, Wei, Liao, Min, Heyen, Jonathan, Buetow, Bernard, Pillai, Smitha, Matsumoto, Diane, Chaparro-Riggers, Javier, Salek-Ardakani, Shahram, Qu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264827/
https://www.ncbi.nlm.nih.gov/pubmed/32474414
http://dx.doi.org/10.1136/jitc-2020-000624

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264827/
https://www.ncbi.nlm.nih.gov/pubmed/32474414
http://dx.doi.org/10.1136/jitc-2020-000624

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