Interplay between glucocorticoids and tumor-infiltrating lymphocytes on the prognosis of adrenocortical carcinoma

BACKGROUND: Adrenocortical carcinoma (ACC) is a rare endocrine malignancy. Tumor-related glucocorticoid excess is present in ~60% of patients and associated with particularly poor prognosis. Results of first clinical trials using immune checkpoint inhibitors were heterogeneous. Here we characterize...

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Detalles Bibliográficos
Autores principales: Landwehr, Laura-Sophie, Altieri, Barbara, Schreiner, Jochen, Sbiera, Iuliu, Weigand, Isabel, Kroiss, Matthias, Fassnacht, Martin, Sbiera, Silviu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Basic Tumor Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264832/
https://www.ncbi.nlm.nih.gov/pubmed/32474412
http://dx.doi.org/10.1136/jitc-2019-000469

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264832/
https://www.ncbi.nlm.nih.gov/pubmed/32474412
http://dx.doi.org/10.1136/jitc-2019-000469

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