Medin Oligomer Membrane Pore Formation: A Potential Mechanism of Vascular Dysfunction

Medin, a 50-amino-acid cleavage product of the milk fat globule-EGF factor 8 protein, is one of the most common forms of localized amyloid found in the vasculature of individuals older than 50 years. Medin induces endothelial dysfunction and vascular inflammation, yet despite its prevalence in the h...

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Detalles Bibliográficos
Autores principales: Younger, Scott, Jang, Hyunbum, Davies, Hannah A., Niemiec, Martin J., Garcia, Joe G.N., Nussinov, Ruth, Migrino, Raymond Q., Madine, Jillian, Arce, Fernando T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264854/
https://www.ncbi.nlm.nih.gov/pubmed/32402244
http://dx.doi.org/10.1016/j.bpj.2020.04.026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264854/
https://www.ncbi.nlm.nih.gov/pubmed/32402244
http://dx.doi.org/10.1016/j.bpj.2020.04.026

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