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CD3(+) T cells are critical for the resolution of comorbid inflammatory pain and depression-like behavior

BACKGROUND: Chronic pain and depression often co-occur. The mechanisms underlying this comorbidity are incompletely understood. Here, we investigated the role of CD3(+) T cells in an inflammatory model of comorbid persistent mechanical allodynia, spontaneous pain, and depression-like behavior in mic...

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Detalles Bibliográficos
Autores principales: Laumet, Geoffroy, Edralin, Jules D., Dantzer, Robert, Heijnen, Cobi J., Kavelaars, Annemieke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264986/
https://www.ncbi.nlm.nih.gov/pubmed/32510006
http://dx.doi.org/10.1016/j.ynpai.2020.100043