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Identification of the novel polymorphisms and potential genetic features of the prion protein gene (PRNP) in horses, a prion disease-resistant animal

Prion diseases, a protein misfolded disorder (PMD) caused by misfolded prion protein (PrP(Sc)), present in a wide variety of hosts, ranging from ungulates to humans. To date, prion infections have not been reported in horses, which are well-known as prion disease-resistant animals. Several studies h...

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Detalles Bibliográficos
Autores principales: Kim, Yong-Chan, Won, Sae-Young, Do, Kyoungtag, Jeong, Byung-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265282/
https://www.ncbi.nlm.nih.gov/pubmed/32488112
http://dx.doi.org/10.1038/s41598-020-65731-5