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Dscam2 suppresses synaptic strength through a PI3K-dependent endosomal pathway

Dscam2 is a cell surface protein required for neuronal development in Drosophila; it can promote neural wiring through homophilic recognition that leads to either adhesion or repulsion between neurites. Here, we report that Dscam2 also plays a post-developmental role in suppressing synaptic strength...

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Detalles Bibliográficos
Autores principales: Odierna, G. Lorenzo, Kerwin, Sarah K., Harris, Lucy E., Shin, Grace Ji-eun, Lavidis, Nickolas A., Noakes, Peter G., Millard, S. Sean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265308/
https://www.ncbi.nlm.nih.gov/pubmed/32259198
http://dx.doi.org/10.1083/jcb.201909143