Mitochondrial translation and dynamics synergistically extend lifespan in C. elegans through HLH-30

Mitochondrial form and function are closely interlinked in homeostasis and aging. Inhibiting mitochondrial translation is known to increase lifespan in C. elegans, and is accompanied by a fragmented mitochondrial network. However, whether this link between mitochondrial translation and morphology is...

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Detalles Bibliográficos
Autores principales: Liu, Yasmine J., McIntyre, Rebecca L., Janssens, Georges E., Williams, Evan G., Lan, Jiayi, van Weeghel, Michel, Schomakers, Bauke, van der Veen, Henk, van der Wel, Nicole N., Yao, Pallas, Mair, William B., Aebersold, Ruedi, MacInnes, Alyson W., Houtkooper, Riekelt H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265311/
https://www.ncbi.nlm.nih.gov/pubmed/32259199
http://dx.doi.org/10.1083/jcb.201907067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265311/
https://www.ncbi.nlm.nih.gov/pubmed/32259199
http://dx.doi.org/10.1083/jcb.201907067

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