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TRPA1-dependent calcium transients and CGRP release in DRG neurons require extracellular calcium

Shang et al. (2016. J. Cell Biol. https://doi.org/10.1083/jcb.201603081) reported that activation of lysosomal TRPA1 channels led to intracellular calcium transients and CGRP release from DRG neurons. We argue that both findings are more likely due to influx of insufficiently buffered extracellular...

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Detalles Bibliográficos
Autores principales: Gebhardt, Lisa A., Kichko, Tetyana I., Fischer, Michael J.M., Reeh, Peter W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265312/
https://www.ncbi.nlm.nih.gov/pubmed/32434221
http://dx.doi.org/10.1083/jcb.201702151