KIF14 controls ciliogenesis via regulation of Aurora A and is important for Hedgehog signaling

Primary cilia play critical roles in development and disease. Their assembly and disassembly are tightly coupled to cell cycle progression. Here, we present data identifying KIF14 as a regulator of cilia formation and Hedgehog (HH) signaling. We show that RNAi depletion of KIF14 specifically leads t...

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Detalles Bibliográficos
Autores principales: Pejskova, Petra, Reilly, Madeline Louise, Bino, Lucia, Bernatik, Ondrej, Dolanska, Linda, Ganji, Ranjani Sri, Zdrahal, Zbynek, Benmerah, Alexandre, Cajanek, Lukas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265313/
https://www.ncbi.nlm.nih.gov/pubmed/32348467
http://dx.doi.org/10.1083/jcb.201904107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265313/
https://www.ncbi.nlm.nih.gov/pubmed/32348467
http://dx.doi.org/10.1083/jcb.201904107

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