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Sterol biosensor reveals LAM-family Ltc1-dependent sterol flow to endosomes upon Arp2/3 inhibition

Sterols are crucial components of biological membranes, which are synthetized in the ER and accumulate in the plasma membrane (PM). Here, by applying a genetically encoded sterol biosensor (D4H), we visualize a sterol flow between PM and endosomes in the fission yeast Schizosaccharomyces pombe. Usin...

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Detalles Bibliográficos
Autores principales: Marek, Magdalena, Vincenzetti, Vincent, Martin, Sophie G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265315/
https://www.ncbi.nlm.nih.gov/pubmed/32320462
http://dx.doi.org/10.1083/jcb.202001147