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Autophagosome biogenesis: From membrane growth to closure

Autophagosome biogenesis involves de novo formation of a membrane that elongates to sequester cytoplasmic cargo and closes to form a double-membrane vesicle (an autophagosome). This process has remained enigmatic since its initial discovery >50 yr ago, but our understanding of the mechanisms invo...

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Detalles Bibliográficos
Autores principales: Melia, Thomas J., Lystad, Alf H., Simonsen, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265318/
https://www.ncbi.nlm.nih.gov/pubmed/32357219
http://dx.doi.org/10.1083/jcb.202002085