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Prolonged mitosis results in structurally aberrant and over-elongated centrioles

Centrioles are precisely built microtubule-based structures that assemble centrosomes and cilia. Aberrations in centriole structure are common in tumors, yet how these aberrations arise is unknown. Analysis of centriole structure is difficult because it requires demanding electron microscopy. Here w...

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Detalles Bibliográficos
Autores principales: Kong, Dong, Sahabandu, Natalie, Sullenberger, Catherine, Vásquez-Limeta, Alejandra, Luvsanjav, Delgermaa, Lukasik, Kimberly, Loncarek, Jadranka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265320/
https://www.ncbi.nlm.nih.gov/pubmed/32271878
http://dx.doi.org/10.1083/jcb.201910019