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Phosphorylation of the microtubule-severing AAA+ enzyme Katanin regulates C. elegans embryo development

The evolutionarily conserved microtubule (MT)-severing AAA-ATPase enzyme Katanin is emerging as a critical regulator of MT dynamics. In Caenorhabditis elegans, Katanin MT-severing activity is essential for meiotic spindle assembly but is toxic for the mitotic spindle. Here we analyzed Katanin dynami...

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Detalles Bibliográficos
Autores principales: Joly, Nicolas, Beaumale, Eva, Van Hove, Lucie, Martino, Lisa, Pintard, Lionel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265321/
https://www.ncbi.nlm.nih.gov/pubmed/32412594
http://dx.doi.org/10.1083/jcb.201912037