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Mitochondrial translation, dynamics, and lysosomes combine to extend lifespan
In this issue, Liu et al. (2019. J. Cell. Biol. https://doi.org/10.1083/jcb.201907067) find that the inhibition of mitochondrial ribosomes in combination with impaired mitochondrial fission or fusion increases C. elegans lifespan by activating the transcription factor HLH-30, which promotes lysosoma...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265329/ https://www.ncbi.nlm.nih.gov/pubmed/32434220 http://dx.doi.org/10.1083/jcb.202005084 |