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Mitochondrial translation, dynamics, and lysosomes combine to extend lifespan

In this issue, Liu et al. (2019. J. Cell. Biol. https://doi.org/10.1083/jcb.201907067) find that the inhibition of mitochondrial ribosomes in combination with impaired mitochondrial fission or fusion increases C. elegans lifespan by activating the transcription factor HLH-30, which promotes lysosoma...

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Detalles Bibliográficos
Autores principales: Ali, Levi, Haynes, Cole M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265329/
https://www.ncbi.nlm.nih.gov/pubmed/32434220
http://dx.doi.org/10.1083/jcb.202005084