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Cyclin B1-Cdk1 facilitates MAD1 release from the nuclear pore to ensure a robust spindle checkpoint

How the cell rapidly and completely reorganizes its architecture when it divides is a problem that has fascinated researchers for almost 150 yr. We now know that the core regulatory machinery is highly conserved in eukaryotes, but how these multiple protein kinases, protein phosphatases, and ubiquit...

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Detalles Bibliográficos
Autores principales: Jackman, Mark, Marcozzi, Chiara, Barbiero, Martina, Pardo, Mercedes, Yu, Lu, Tyson, Adam L., Choudhary, Jyoti S., Pines, Jonathon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265330/
https://www.ncbi.nlm.nih.gov/pubmed/32236513
http://dx.doi.org/10.1083/jcb.201907082