Substitution of warthog NF-κB motifs into RELA of domestic pigs is not sufficient to confer resilience to African swine fever virus

African swine fever virus (ASFV) causes a lethal, haemorrhagic disease in domestic swine that threatens pig production across the globe. Unlike domestic pigs, warthogs, which are wildlife hosts of the virus, do not succumb to the lethal effects of infection. There are three amino acid differences be...

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Detalles Bibliográficos
Autores principales: McCleary, Stephen, Strong, Rebecca, McCarthy, Ronan R., Edwards, Jane C., Howes, Emma L., Stevens, Lisa M., Sánchez-Cordón, Pedro J., Núñez, Alejandro, Watson, Samantha, Mileham, Alan J., Lillico, Simon G., Tait-Burkard, Christine, Proudfoot, Chris, Ballantyne, Maeve, Whitelaw, C. Bruce A., Steinbach, Falko, Crooke, Helen R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265332/
https://www.ncbi.nlm.nih.gov/pubmed/32488046
http://dx.doi.org/10.1038/s41598-020-65808-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265332/
https://www.ncbi.nlm.nih.gov/pubmed/32488046
http://dx.doi.org/10.1038/s41598-020-65808-1

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