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Substitution of warthog NF-κB motifs into RELA of domestic pigs is not sufficient to confer resilience to African swine fever virus
African swine fever virus (ASFV) causes a lethal, haemorrhagic disease in domestic swine that threatens pig production across the globe. Unlike domestic pigs, warthogs, which are wildlife hosts of the virus, do not succumb to the lethal effects of infection. There are three amino acid differences be...
Autores principales: | McCleary, Stephen, Strong, Rebecca, McCarthy, Ronan R., Edwards, Jane C., Howes, Emma L., Stevens, Lisa M., Sánchez-Cordón, Pedro J., Núñez, Alejandro, Watson, Samantha, Mileham, Alan J., Lillico, Simon G., Tait-Burkard, Christine, Proudfoot, Chris, Ballantyne, Maeve, Whitelaw, C. Bruce A., Steinbach, Falko, Crooke, Helen R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265332/ https://www.ncbi.nlm.nih.gov/pubmed/32488046 http://dx.doi.org/10.1038/s41598-020-65808-1 |
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