Evaluation of anti-biofilm activity of acidic amino acids and synergy with ciprofloxacin on Staphylococcus aureus biofilms

Acidic amino acids, aspartic acid (Asp) and glutamic acid (Glu) can enhance the solubility of many poorly soluble drugs including ciprofloxacin (Cip). One of the mechanisms of resistance within a biofilm is retardation of drug diffusion due to poor penetration across the matrix. To overcome this cha...

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Detalles Bibliográficos
Autores principales: Warraich, Annsar A., Mohammed, Afzal R., Perrie, Yvonne, Hussain, Majad, Gibson, Hazel, Rahman, Ayesha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265346/
https://www.ncbi.nlm.nih.gov/pubmed/32488138
http://dx.doi.org/10.1038/s41598-020-66082-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265346/
https://www.ncbi.nlm.nih.gov/pubmed/32488138
http://dx.doi.org/10.1038/s41598-020-66082-x

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