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Zika Virus NS3 Protease Pharmacophore Anchor Model and Drug Discovery

Zika virus (ZIKV) of the flaviviridae family, is the cause of emerging infections characterized by fever, Guillain-Barré syndrome (GBS) in adults and microcephaly in newborns. There exists an urgent unmet clinical need for anti-ZIKV drugs for the treatment of infected individuals. In the current wor...

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Detalles Bibliográficos
Autores principales: Pathak, Nikhil, Kuo, Yi-Ping, Chang, Teng-Yuan, Huang, Chin-Ting, Hung, Hui-Chen, Hsu, John Tsu-An, Yu, Guann-Yi, Yang, Jinn-Moon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265434/
https://www.ncbi.nlm.nih.gov/pubmed/32488021
http://dx.doi.org/10.1038/s41598-020-65489-w