Ultra-rapid glutathionylation of chymotrypsinogen in its molten globule-like conformation: A comparison to archaeal proteins

Chymotrypsinogen, when reduced and taken to its molten globule-like conformation, displays a single cysteine with an unusual kinetic propensity toward oxidized glutathione (GSSG) and other organic thiol reagents. A single residue, identified by mass spectrometry like Cys1, reacts with GSSG about 140...

Descripción completa

Detalles Bibliográficos
Autores principales: Bocedi, Alessio, Gambardella, Giorgia, Cattani, Giada, Bartolucci, Simonetta, Limauro, Danila, Pedone, Emilia, Iavarone, Federica, Castagnola, Massimo, Ricci, Giorgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265447/
https://www.ncbi.nlm.nih.gov/pubmed/32488029
http://dx.doi.org/10.1038/s41598-020-65696-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265447/
https://www.ncbi.nlm.nih.gov/pubmed/32488029
http://dx.doi.org/10.1038/s41598-020-65696-5

Ejemplares similares