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Ultra-rapid glutathionylation of chymotrypsinogen in its molten globule-like conformation: A comparison to archaeal proteins

Chymotrypsinogen, when reduced and taken to its molten globule-like conformation, displays a single cysteine with an unusual kinetic propensity toward oxidized glutathione (GSSG) and other organic thiol reagents. A single residue, identified by mass spectrometry like Cys1, reacts with GSSG about 140...

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Detalles Bibliográficos
Autores principales:	Bocedi, Alessio, Gambardella, Giorgia, Cattani, Giada, Bartolucci, Simonetta, Limauro, Danila, Pedone, Emilia, Iavarone, Federica, Castagnola, Massimo, Ricci, Giorgio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265447/ https://www.ncbi.nlm.nih.gov/pubmed/32488029 http://dx.doi.org/10.1038/s41598-020-65696-5

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