Multiplexed relative and absolute quantitative immunopeptidomics reveals MHC I repertoire alterations induced by CDK4/6 inhibition

Peptides bound to class I major histocompatibility complexes (MHC) play a critical role in immune cell recognition and can trigger an antitumor immune response in cancer. Surface MHC levels can be modulated by anticancer agents, altering immunity. However, understanding the peptide repertoire’s resp...

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Detalles Bibliográficos
Autores principales: Stopfer, Lauren E., Mesfin, Joshua M., Joughin, Brian A., Lauffenburger, Douglas A., White, Forest M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265461/
https://www.ncbi.nlm.nih.gov/pubmed/32488085
http://dx.doi.org/10.1038/s41467-020-16588-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265461/
https://www.ncbi.nlm.nih.gov/pubmed/32488085
http://dx.doi.org/10.1038/s41467-020-16588-9

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