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The tumour microenvironment shapes dendritic cell plasticity in a human organotypic melanoma culture

The tumour microenvironment (TME) forms a major obstacle in effective cancer treatment and for clinical success of immunotherapy. Conventional co-cultures have shed light onto multiple aspects of cancer immunobiology, but they are limited by the lack of physiological complexity. We develop a human o...

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Detalles Bibliográficos
Autores principales: Di Blasio, S., van Wigcheren, G. F., Becker, A., van Duffelen, A., Gorris, M., Verrijp, K., Stefanini, I., Bakker, G. J., Bloemendal, M., Halilovic, A., Vasaturo, A., Bakdash, G., Hato, S. V., de Wilt, J. H. W., Schalkwijk, J., de Vries, I. J. M., Textor, J. C., van den Bogaard, E. H., Tazzari, M., Figdor, C. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265463/
https://www.ncbi.nlm.nih.gov/pubmed/32488012
http://dx.doi.org/10.1038/s41467-020-16583-0