Body weight algorithm predicts humane endpoint in an intracranial rat glioma model

Humane endpoint determination is fundamental in animal experimentation. Despite commonly accepted endpoint criteria for intracranial tumour models (20% body weight loss and deteriorated clinical score) some animals still die before being euthanized in current research. We here systematically evaluat...

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Detalles Bibliográficos
Autores principales: Helgers, Simeon O. A., Talbot, Steven R., Riedesel, Ann-Kristin, Wassermann, Laura, Wu, Zhiqun, Krauss, Joachim K., Häger, Christine, Bleich, André, Schwabe, Kerstin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265476/
https://www.ncbi.nlm.nih.gov/pubmed/32488031
http://dx.doi.org/10.1038/s41598-020-65783-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265476/
https://www.ncbi.nlm.nih.gov/pubmed/32488031
http://dx.doi.org/10.1038/s41598-020-65783-7

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