Stratification and prediction of drug synergy based on target functional similarity

Drug combinations can expand therapeutic options and address cancer’s resistance. However, the combinatorial space is enormous precluding its systematic exploration. Therefore, synergy prediction strategies are essential. We here present an approach to prioritise drug combinations in high-throughput...

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Detalles Bibliográficos
Autores principales: Yang, Mi, Jaaks, Patricia, Dry, Jonathan, Garnett, Mathew, Menden, Michael P., Saez-Rodriguez, Julio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265486/
https://www.ncbi.nlm.nih.gov/pubmed/32487991
http://dx.doi.org/10.1038/s41540-020-0136-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265486/
https://www.ncbi.nlm.nih.gov/pubmed/32487991
http://dx.doi.org/10.1038/s41540-020-0136-x

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