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Direct transfer of tri- and di-fluoroethanol units enabled by radical activation of organosilicon reagents

Trifluoroethanol and difluoroethanol units are important motifs in bioactive molecules, but the methods to direct incorporate these units are limited. Herein, we report two organosilicon reagents for the transfer of trifluoroethanol and difluoroethanol units into molecules. Through intramolecular C-...

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Detalles Bibliográficos
Autores principales: Chen, Xiang, Gong, Xingxing, Li, Zhengyu, Zhou, Gang, Zhu, Zhihong, Zhang, Weilu, Liu, Shanshan, Shen, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265496/
https://www.ncbi.nlm.nih.gov/pubmed/32488003
http://dx.doi.org/10.1038/s41467-020-16380-9