Loss of the transcription factor MAFB limits β-cell derivation from human PSCs

Next generation sequencing studies have highlighted discrepancies in β-cells which exist between mice and men. Numerous reports have identified MAF BZIP Transcription Factor B (MAFB) to be present in human β-cells postnatally, while its expression is restricted to embryonic and neo-natal β-cells in...

Descripción completa

Detalles Bibliográficos
Autores principales: Russell, Ronan, Carnese, Phichitpol P., Hennings, Thomas G., Walker, Emily M., Russ, Holger A., Liu, Jennifer S., Giacometti, Simone, Stein, Roland, Hebrok, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265500/
https://www.ncbi.nlm.nih.gov/pubmed/32488111
http://dx.doi.org/10.1038/s41467-020-16550-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265500/
https://www.ncbi.nlm.nih.gov/pubmed/32488111
http://dx.doi.org/10.1038/s41467-020-16550-9

Ejemplares similares