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Dendritic cells-derived interferon-λ1 ameliorated inflammatory bone destruction through inhibiting osteoclastogenesis

Bone infection contributing to inflammatory osteolysis is common in orthopedic surgery. The dynamic balance between bone formation and bone resorption is destroyed due to excessive osteoclast fusion and differentiation, which results in severe bone matrix loss. Many therapeutic approaches that restr...

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Detalles Bibliográficos
Autores principales: Chen, Yueqi, Wang, Yiran, Tang, Ruohui, Yang, Jing, Dou, Ce, Dong, Yutong, Sun, Dong, Zhang, Chengmin, Zhang, Lincheng, Tang, Yong, Dai, Qijie, Luo, Fei, Xu, Jianzhong, Dong, Shiwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265503/
https://www.ncbi.nlm.nih.gov/pubmed/32488049
http://dx.doi.org/10.1038/s41419-020-2612-z