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Type I interferon sensing unlocks dormant adipocyte inflammatory potential

White adipose tissue inflammation, in part via myeloid cell contribution, is central to obesity pathogenesis. Mechanisms regulating adipocyte inflammatory potential and consequent impact of such inflammation in disease pathogenesis remain poorly defined. We show that activation of the type I interfe...

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Detalles Bibliográficos
Autores principales: Chan, Calvin C., Damen, Michelle S. M. A., Moreno-Fernandez, Maria E., Stankiewicz, Traci E., Cappelletti, Monica, Alarcon, Pablo C., Oates, Jarren R., Doll, Jessica R., Mukherjee, Rajib, Chen, Xiaoting, Karns, Rebekah, Weirauch, Matthew T., Helmrath, Michael A., Inge, Thomas H., Divanovic, Senad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265526/
https://www.ncbi.nlm.nih.gov/pubmed/32488081
http://dx.doi.org/10.1038/s41467-020-16571-4