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Up regulation of the Hippo signalling effector YAP1 is linked to early biochemical recurrence in prostate cancers

The transcriptional coactivator YAP1 controls the balance between cell proliferation and apoptosis. YAP1 overexpression is linked to poor prognosis in many cancer types, yet its role in prostate cancer is unknown. Here, we applied YAP1 immunohistochemistry to a tissue microarray containing 17,747 cl...

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Detalles Bibliográficos
Autores principales: Marx, Andreas, Schumann, Aljoscha, Höflmayer, Doris, Bady, Elena, Hube-Magg, Claudia, Möller, Katharina, Tsourlakis, Maria Christina, Steurer, Stefan, Büscheck, Franziska, Eichenauer, Till, Clauditz, Till S., Graefen, Markus, Simon, Ronald, Sauter, Guido, Izbicki, Jakob R., Huland, Hartwig, Heinzer, Hans, Haese, Alexander, Schlomm, Thorsten, Bernreuther, Christian, Lebok, Patrick, Polonski, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265544/
https://www.ncbi.nlm.nih.gov/pubmed/32488048
http://dx.doi.org/10.1038/s41598-020-65772-w