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Up regulation of the Hippo signalling effector YAP1 is linked to early biochemical recurrence in prostate cancers
The transcriptional coactivator YAP1 controls the balance between cell proliferation and apoptosis. YAP1 overexpression is linked to poor prognosis in many cancer types, yet its role in prostate cancer is unknown. Here, we applied YAP1 immunohistochemistry to a tissue microarray containing 17,747 cl...
Autores principales: | Marx, Andreas, Schumann, Aljoscha, Höflmayer, Doris, Bady, Elena, Hube-Magg, Claudia, Möller, Katharina, Tsourlakis, Maria Christina, Steurer, Stefan, Büscheck, Franziska, Eichenauer, Till, Clauditz, Till S., Graefen, Markus, Simon, Ronald, Sauter, Guido, Izbicki, Jakob R., Huland, Hartwig, Heinzer, Hans, Haese, Alexander, Schlomm, Thorsten, Bernreuther, Christian, Lebok, Patrick, Polonski, Adam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265544/ https://www.ncbi.nlm.nih.gov/pubmed/32488048 http://dx.doi.org/10.1038/s41598-020-65772-w |
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