UPLC-Tandem Mass Spectrometry for Quantification of Busulfan in Human Plasma: Application to Therapeutic Drug Monitoring

Busulfan (Bu) is an alkylating agent commonly used in preparative regimens for hematologic malignant and non-malignant patients undergoing hematopoietic stem cell transplantation (HSCT). The objective of the present study was to develop an UPLC-MS/MS method for quantification of Bu in human plasma....

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Detalles Bibliográficos
Autores principales: Matar, Kamal M., Alshemmari, Salem H., Refaat, Samar, Anwar, Alia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265561/
https://www.ncbi.nlm.nih.gov/pubmed/32488110
http://dx.doi.org/10.1038/s41598-020-65919-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265561/
https://www.ncbi.nlm.nih.gov/pubmed/32488110
http://dx.doi.org/10.1038/s41598-020-65919-9

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