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TNF-alpha-induced microglia activation requires miR-342: impact on NF-kB signaling and neurotoxicity

Growing evidences suggest that sustained neuroinflammation, caused by microglia overactivation, is implicated in the development and aggravation of several neurological and psychiatric disorders. In some pathological conditions, microglia produce increased levels of cytotoxic and inflammatory mediat...

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Detalles Bibliográficos
Autores principales: Brás, João Paulo, Bravo, Joana, Freitas, Jaime, Barbosa, Mário Adolfo, Santos, Susana Gomes, Summavielle, Teresa, Almeida, Maria Inês
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265562/
https://www.ncbi.nlm.nih.gov/pubmed/32488063
http://dx.doi.org/10.1038/s41419-020-2626-6