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TNF-alpha-induced microglia activation requires miR-342: impact on NF-kB signaling and neurotoxicity
Growing evidences suggest that sustained neuroinflammation, caused by microglia overactivation, is implicated in the development and aggravation of several neurological and psychiatric disorders. In some pathological conditions, microglia produce increased levels of cytotoxic and inflammatory mediat...
Autores principales: | Brás, João Paulo, Bravo, Joana, Freitas, Jaime, Barbosa, Mário Adolfo, Santos, Susana Gomes, Summavielle, Teresa, Almeida, Maria Inês |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265562/ https://www.ncbi.nlm.nih.gov/pubmed/32488063 http://dx.doi.org/10.1038/s41419-020-2626-6 |
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