Cargando…

Stage-Specific Requirement for Eomes in Mature NK Cell Homeostasis and Cytotoxicity

Natural killer (NK) cells are cytotoxic innate lymphoid cells (ILCs) that mediate antiviral and antitumor responses and require the transcriptional regulator Eomesodermin (Eomes) for early development. However, the role of Eomes and its molecular program in mature NK cell biology is unclear. To addr...

Descripción completa

Detalles Bibliográficos
Autores principales: Wagner, Julia A., Wong, Pamela, Schappe, Timothy, Berrien-Elliott, Melissa M., Cubitt, Celia, Jaeger, Natalia, Lee, Madeline, Keppel, Cassie R., Marin, Nancy D., Foltz, Jennifer A., Marsala, Lynne, Neal, Carly C., Sullivan, Ryan P., Schneider, Stephanie E., Keppel, Molly P., Saucier, Nermina, Cooper, Megan A., Fehniger, Todd A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265846/
https://www.ncbi.nlm.nih.gov/pubmed/32492428
http://dx.doi.org/10.1016/j.celrep.2020.107720