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Molecular mechanism of BK channel activation by the smooth muscle relaxant NS11021
Large-conductance Ca(2+)-activated K(+) channels (BK channels) are activated by cytosolic calcium and depolarized membrane potential under physiological conditions. Thus, these channels control electrical excitability in neurons and smooth muscle by gating K(+) efflux and hyperpolarizing the membran...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7266150/ https://www.ncbi.nlm.nih.gov/pubmed/32221543 http://dx.doi.org/10.1085/jgp.201912506 |