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Molecular mechanism of BK channel activation by the smooth muscle relaxant NS11021

Large-conductance Ca(2+)-activated K(+) channels (BK channels) are activated by cytosolic calcium and depolarized membrane potential under physiological conditions. Thus, these channels control electrical excitability in neurons and smooth muscle by gating K(+) efflux and hyperpolarizing the membran...

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Detalles Bibliográficos
Autores principales:	Rockman, Michael E., Vouga, Alexandre G., Rothberg, Brad S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7266150/ https://www.ncbi.nlm.nih.gov/pubmed/32221543 http://dx.doi.org/10.1085/jgp.201912506

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