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HIV-1 spliced RNAs display transcription start site bias

Human immunodeficiency virus type 1 (HIV-1) transcripts have three fates: to serve as genomic RNAs, unspliced mRNAs, or spliced subgenomic mRNAs. Recent structural studies have shown that sequences near the 5′ end of HIV-1 RNA can adopt at least two alternate three-dimensional conformations, and tha...

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Detalles Bibliográficos
Autores principales: Esquiaqui, Jackie M., Kharytonchyk, Siahrei, Drucker, Darra, Telesnitsky, Alice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7266155/
https://www.ncbi.nlm.nih.gov/pubmed/32205324
http://dx.doi.org/10.1261/rna.073650.119