YTHDF2 destabilizes m(6)A-modified neural-specific RNAs to restrain differentiation in induced pluripotent stem cells

N(6)-methyladenosine (m(6)A) is an abundant post-transcriptional modification that can impact RNA fate via interactions with m(6)A-specific RNA binding proteins. Despite accumulating evidence that m(6)A plays an important role in modulating pluripotency, the influence of m(6)A reader proteins in plu...

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Detalles Bibliográficos
Autores principales: Heck, Adam M., Russo, Joseph, Wilusz, Jeffrey, Nishimura, Erin Osborne, Wilusz, Carol J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7266156/
https://www.ncbi.nlm.nih.gov/pubmed/32169943
http://dx.doi.org/10.1261/rna.073502.119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7266156/
https://www.ncbi.nlm.nih.gov/pubmed/32169943
http://dx.doi.org/10.1261/rna.073502.119

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