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YTHDF2 destabilizes m(6)A-modified neural-specific RNAs to restrain differentiation in induced pluripotent stem cells
N(6)-methyladenosine (m(6)A) is an abundant post-transcriptional modification that can impact RNA fate via interactions with m(6)A-specific RNA binding proteins. Despite accumulating evidence that m(6)A plays an important role in modulating pluripotency, the influence of m(6)A reader proteins in plu...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7266156/ https://www.ncbi.nlm.nih.gov/pubmed/32169943 http://dx.doi.org/10.1261/rna.073502.119 |