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Histone methyltransferase SETD1A interacts with HIF1α to enhance glycolysis and promote cancer progression in gastric cancer

Growing tumors alter their metabolic profiles to support the increased cell proliferation. SETD1A, a histone lysine methyltransferase which specifically methylates H3K4, plays important roles in both normal cell and cancer cell functions. However, the function of SETD1A in gastric cancer (GC) progre...

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Detalles Bibliográficos
Autores principales: Wu, Jugang, Chai, Hongjuan, Xu, Xin, Yu, Jiwei, Gu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7266269/
https://www.ncbi.nlm.nih.gov/pubmed/32291851
http://dx.doi.org/10.1002/1878-0261.12689