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Complex context relationships between DNA methylation and accessibility, histone marks, and hTERT gene expression in acute promyelocytic leukemia cells: perspectives for all‐trans retinoic acid in cancer therapy

Telomerase (hTERT) reactivation and sustained expression is a key event in the process of cellular transformation. Therefore, the identification of the mechanisms regulating hTERT expression is of great interest for the development of new anticancer therapies. Although the epigenetic state of hTERT...

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Detalles Bibliográficos
Autores principales: Garsuault, Delphine, Bouyer, Claire, Nguyen, Eric, Kandhari, Rohan, Prochazkova‐Carlotti, Martina, Chevret, Edith, Forgez, Patricia, Ségal‐Bendirdjian, Evelyne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7266276/
https://www.ncbi.nlm.nih.gov/pubmed/32239597
http://dx.doi.org/10.1002/1878-0261.12681