Epigallocatechin-3-Gallate Protects H(2)O(2)-Induced Nucleus Pulposus Cell Apoptosis and Inflammation by Inhibiting cGAS/Sting/NLRP3 Activation

BACKGROUND: Intervertebral disc degeneration (IDD) is the most common diagnosis of patients with lower back pain. IDD is the underlying lesion of many spinal degenerative diseases; however, the role of cGAS/Sting/NLRP3 pathway and epigallocatechin gallate (EGCG) in the development of IDD remained un...

Descripción completa

Detalles Bibliográficos
Autores principales: Tian, Yixing, Bao, Zhaohua, Ji, Yiming, Mei, Xin, Yang, Huilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7266312/
https://www.ncbi.nlm.nih.gov/pubmed/32546974
http://dx.doi.org/10.2147/DDDT.S251623

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7266312/
https://www.ncbi.nlm.nih.gov/pubmed/32546974
http://dx.doi.org/10.2147/DDDT.S251623

Ejemplares similares